Washington: a fresh study showed that cell proliferation actually protects HIV-infected cells alive in infected people, including the subsequent passage of antiretroviral therapy (art). The study is published in the journal Nature Communications journal. Cell proliferation is a process that results in a rise in the number of cells, in which the balance between cell divisions and cell loss happens through death or cell differentiation.

Scientists have tested that lowering cell proliferation has the ability to help reduce the number of infected cells and potentially lead to active healing from HIV. A research team in the vaccine and communicable disease Department at Fred Hutchinson cancer Research center combined mathematical models and immunological awareness to understand the genetic signature of HIV-infected cells.

"Our alignment was inspired by the environment," said principal surveyor Dan Reeves. "We adapted the tools for a more near-reality property of the reservoir of HIV - infected cells, removing the generation device from the ratios of original and similar genetic signatures," Reeves added.

When HIV infects a healthy cell, it inserts its own personal DNA into the human chromosome, leaving behind a unique genetic signature. If microbial replication was a prerequisite for sheltered reservoirs of HIV, scientists have presented, in fact, that this genetic signature will keep the original integration websites and all sorts of mutations in the DNA of infected cells.

Art has been effective in helping HIV-positive people produce a healthy lifestyle since the late 1990s. Since then, HIV scientists have been working to understand why the reservoirs of HIV-infected immune cells remain at a low level during the healing of art, and how to identify and clean infected cells.

"We see Parallels in achieving active ways of healing both in HIV, for example, and in cancer; for example, the problems of remission and relapse, and how combination therapy has the ability to be successful in bringing any disease to undetectable value in the body," said another researcher, Josh Schiffer.

Schiffer and his colleague are conducting a clinical test to find out whether the lymphocytic antiproliferative product Mycophenolate Mofetil (MMF) can be effective in stopping the proliferation of HIV-infected immune cells in people who have undergone art. It is important to be able to cure HIV.