The procedure, evaluated by nice and applied in research conducted by the Birmingham Institute, has been hailed as an exciting development in increasing the number of liver that has the ability to be safely applied for transplantation.

Perfusion machine has the ability to maintain longer the viability of the donor liver for transplantation. Installation reduces the rate of tissue destruction, which happens later removal of the liver from the donor, and extends the life of the liver savings before transplantation.

Fashion configurations have all chances to still allow the liver to be flushed with blood at body temperature and supplied with oxygen, medications and nourishing drugs allowing its own viability and function to be evaluated.

There is an expectation, in fact, that machine perfusion has the ability to increase the number of organs used for transplantation, saving more lives and lowering the waiting lists for liver transplantation.

Liver transplantation is considered a fairly successful cure for end-stage liver disease, which kills 11,000 people a year in the UK. Mortality from liver disease has increased by 25 % over the decade and continues to rise, while the average age of death from liver disease (in real time 50-59 years) continues to decline.

Now, nice has released a final statement in which the procedure is recommended—machine perfusion ex-vivo to in vitro storage of the liver for transplantation—which is used in the framework of special agreements as the collection of incremental data about its performance.

The independent Advisory Committee of nice did not identify any serious problems in the field of security.

Doctors conducting the function are required to inform patients about the uncertainty of the performance of the procedure, to comply with the appropriate regulatory and legal requirements of the human tissue authority and are required to include data on all patients with this function in the registry of transplantation NHSBT UK.

NHS England and the commissioners will decide whether they are funding this function. However, studies are already underway in centers across England, covering the study of professionals from the center for liver and gastrointestinal tract studies of the Birmingham Institute at the University of immunology and immunotherapy, Institute hospitals of the Birmingham NHS Trust Foundation in the clinic of Queen Elizabeth Birmingham and the state University of medical studies (NIHR) Birmingham mid biomedical studies.

Notable doctor of the Institute of Birmingham Darius Mirza, consultant transplant surgeon at the Institute clinics of the Birmingham NHS Foundation, said: "in the 30 years that I participated in the transplantation, there were 3 or 4 actions that were game changers, and I certainly have no doubt that we are looking at a game changer that will change the method, which we practice saving and organ transplantation.

"This is already replacing the practice in the centers that have been able to apply this technology or in the framework of clinical testing, or as part of the expansion of the evaluation of proposals."

Dr. Kevin Harris, program Director and clinical Advisor of the intervention procedures program in nice, said: "this procedure gives hope to patients who need a liver transplant. It invites another way to protect the liver, and to predetermine whether the livers that had the opportunity before to be provided inappropriately, it is possible to apply non-dangerously.

"The latest confirmations reviewed by the NICE Committee came to the conclusion that the procedure works perfectly and is not dangerous for patients who were fully informed about the risks and superiority. Clinicians are required to obtain the encouragement of managing their own trust And to record all of these procedures in the data base.

"Applying this function, more patients in the waiting list for organ transplantation have all chances to get a chance for transplantation and there-potentially prolong their own life."

Sue Bennett, 45, a mother of three children from Ranton in Staffordshire, underwent liver transplantation with the introduction of this fresh method in 2015.

She said: "I signed up for the trial, not taking into account the fact that I will be one of the first to carry out this function in the country. I was pretty sick before the transplant. I lost weight, had no opportunity to fall asleep, and the quality of my life was quite low.

"I had a transplant later such as the clinic found a donor who was suitable. The liver was kept current with the support of this procedure in the direction of the night, and I was able to arrange an operation for the coming day. 9 days later I returned home.

"The transplant changed my life. I signed up for the gym, pulled a fit and went back to work and did some volunteer work for the Staffordshire wanted and rescue team and I still compete at the state and international levels in transplant Games as a member of the GB transplant team.

"My life is unimaginably great. I'm not quite sick, quite happy and quite active. I guess I'm pretty lucky."

John Forsythe, Deputy medical Director of NHS Blood and Transplant, said: "there has been a large number of studies in the field of methods of storage and perfusion, which enable us to evaluate valuable donor organs, for example, and to increase their function. This has the potential to mean that the organ actually works than any other and improves the results of transplantation.

"Almost all of the main researchers in the field of methods of storage and perfusion of the transplant are present in England, and it is good to see that the British scientists continue to remain on the frontline in this area.

"Transplantation would have been impossible without the generosity of organ donors and their families."

Vanessa Hebditch, Director of tasks for politicians of the English liver Foundation, said: "every year hundreds of people with progressive liver diseases die in anticipation of transplantation.

"This fresh device highlights the real hope, because it has the ability to make better the results of transplantation and allow the liver, which previously were not applicable for use, and even to increase the time that the liver has the ability to be saved.

"This is an exciting event that has the ability to reduce waiting time and reduce mortality from frequent liver diseases. Subsequently, transplants pacifying the bulk of people continue to produce a full and healthy life, and it's really amazing to see the modification."

In the economic year ended 31 March 2018, there were 1,043 liver transplants in England and 359 patients on the England intensive care transplant list, according to NHS Blood and Transplant data.

The number of patients on the list of intensive transplants reached a ten-year high in 2015, when 611 patients were on the waiting list. However, the tremendous decline associated with the figure of 2018, has the opportunity to be associated with the entry of the state liver supply scheme (NLOS) in March 2018.