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Healing of experimental myocardial predosteregaet Alzheimer's disease in a new study

Healing of experimental myocardial predosteregaet Alzheimer's disease in a new study

Scientists have discovered that the product, which is being developed in real time as a cure for patients with heart attack, still has the ability to be able to prevent Alzheimer's disease.

In not so long ago occurred work, the team from the Institute of southern California has recommended that during the test on animals, the drug has reduced the build-up of toxic peptides and warned the loss of memory — 2 signs of Alzheimer's — in mice.

The results of the study are published In the journal of experimental medicine

Fighting Alzheimer's disease
The study demonstrated, in fact, that 3k3a-APC, at the gene level, a modified version of human blood protein, called activated protein C, has proven beneficial in all sorts of criteria, covering craniocerebral trauma and confused sclerosis. Not least, the researchers involved in the study are actually developing it as a cure for a heart attack because of its ability to reduce intracerebral bleeding in humans.

However, during testing, scientists have noticed that 3K3A-APC, which have qualities that have all chances to prevent Alzheimer's disease.

” Because of its neuroprotective, vasculoprotective, and anti-inflammatory potency in several models of neurological disorders, we studied whether 3K3A-APC still has the ability to defend the brain from the toxic effects of amyloid β-toxin in the mouse Alzheimer's model, " explained Berislav V. Zlokovich of the southern California Institute and times of the study's creators.

They noticed, in fact, that 3K3A-APC significantly reduced the accumulation of amyloid-β, which accumulates in the mouse brain of the Alzheimer's disease model. Scientists have noticed that 3K3A-APC actually overlaps nerve cells from the manufacture of BACE1, an enzyme important for the manufacture of amyloid-β.

Past trials have felt bace1 Abs inhibitors as a treatment for Alzheimer's but scientists believe, in fact, that the fresh experimental drug they are in real time developing has the opportunity to nominate.

Apart from this, at the gene level, the altered protein can help maintain cerebral blood flow and prevent memory loss in mice. It even warned inflammation of the brain, in fact that patients who suffer from neurodegenerative diseases, feel.

Prevention of Alzheimer's disease
Alzheimer's disease is considered to be more common dementia. In 2014, 5 million adults in the United States were diagnosed with the disease. By 2040, the Centers for disease control and prevention predict that the number of cases across the country will almost triple to 14 million..

Scientists believe that 3K3A-APC actually contains the potential to freeze with antiamyloid β for people with early-stage Alzheimer's disease. It's still not healing and now its own effects only observed in mice, but the price of studying in the future research work.

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