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Explore Lulu and Nana, zavlyal, what actually 1st in the world of gene-edited guys

Explore Lulu and Nana, zavlyal, what actually 1st in the world of gene-edited guys

It seems, not for example a long time ago, when a cry was raised over Dolly the sheep, the first animal made by the method of cell cloning. Now, if you believe a Chinese researcher, we have created a leap to animal cloning in order to edit our personal offspring at the genetic level.

The prospector, he Jiankui from Shenzhen, talks, in fact that the Twins, familiar as Lulu and Nana, "came to the universe to cry, like all sorts of other kids" a number of months back, and now homes with their own guardians.

According to the Associated Press, he, along with a Chinese team and the support of a South American scientist who traveled abroad because this DNA change is in real time prohibited in the United States, managed to rewrite and forge the twins ' DNA with the support of the CRISPR gene transformation tool.

Target? Honey configuration and stability to diseases, but just to the microbe of HIV / AIDS.

The embryos provided by seven couples were changed with one successful pregnancy. According to the texts of the researcher, a successful pregnancy, which eventually were seen twins, was achieved with the introduction of human sperm, popular as mark, who is considered a carrier of HIV and "never thought, in fact, that can own guys."

"Grace [the mother] started the pregnancy with the 1st distinction; subsequently, such as we sent the sperm of the spouse in her eggs, we still sent some protein and some memo for genetic surgery," he says. "When Lulu and Nana were just one cell, it removed the door through which HIV seeps to make people sick."

The protein doorway is applied by a gene called CCR5 that permits HIV to enter the cells. Just this gene, the team focused on editing.

He added, in fact, that a number of days through the team conducted gene sequencing, in order to see whether the configuration is rooted. According to the scientist, "the operation was carried out successfully, as expected," and virtually no other gene was changed.

What is not the least, the study was conducted in secret, and so far has not been submitted any 1st document for peer research in the field of genetic sequencing and editing.

The identities of the guardians and children involved in the process - who were regarded by some as insane human experiences and dangerous-were also anonymous.

If these statements prove to be true, it will be a necessary milestone in science, the result of which has the ability to freeze a generation born with a natural resistance to some of the most debilitating diseases. This future, however, still raises a number of ethical questions and the probability of a ticklish slope when it comes to "design" guys and such, in fact, that DNA can-or should-be changed.

The study, which was not autonomously tested, was revealed before the gene editing conference, which is due to begin in Hong Kong on Tuesday.

The tool apparently used to conduct the experiment is popular as a clustered periodically Interspaced short Palindromic repeat (CRISPR/CRISPR-Cas9), a genome editing tool based on a natural editing system in microbes. Applying CRISPR, critical genes have all chances to be disabled.

Scientists around the world are still investigating the likely uses of this tool, but for some, the fake DNA of people, it is likely, came very early.

"It's very premature," said Dr. Eric Topol of the SCRIPPS research broadcasting University in California AP. "We are dealing with human operating instructions. This is really a huge event."

Category: Health | Views: 649 | Added by: hameleons30 | Tags: easybib, Edmodo, Hemophilia, crispr, DNA, 贺建奎, ethics, Gene, Engineering, genotype | Rating: 0.0/0
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