Washington: scientists from the medical faculty of the Virginia Institute have identified a likely comment on the mysterious death of specific brain cells observed in Alzheimer's, Parkinson's and other neurodegenerative diseases.

According to recent studies, cells have all chances to die because of the natural configuration of genes in brain cells, which until recently were listed at the gene level similar.

Variation, called 'somatic mosaicism", has the ability to attribute, why neurons in the temporal lobe die first in Alzheimer's disease, for example, and why dopaminergic neurons die first in Parkinson's disease.

Speaking about this, neuroscientist Michael McConnell said “ "It was a tremendous sincere question in neuroscience, especially with all kinds of neurodegenerative diseases, "adding:" what is selective vulnerability? Exactly that lies in his basis of? And now, when we work on the data, we make guesses, in fact, that all kinds of areas of the brain have all the chances to own all kinds of data garden [variations] in young people, and it makes all kinds of areas for the crisis in later life."

The results of the sudden configuration of the genetic composition of individual brain cells were obtained as a result of studies on schizophrenia McConnell. This invention has the ability to contribute to ascribe not only schizophrenia, but also depression, bipolar disorder, autism and other conditions.

McConnell waited, exactly that this mosaicism will become increase with age, exactly that mutations will become accumulate with the passage of time. The fact that he and his colleague from the Johns Hopkins spotted, straight back from the young people was more of a mosaic at the old least.

Based on the results of the study, McConnell believes that neurons with an important genetic change, familiar as CNV neurons, have all chances to be more vulnerable to death. And it has the ability to attribute idiosyncratic death of specific neurons in all kinds of neurodegenerative diseases. For example, people with a large number of neurons CNV in the temporal lobe has the ability to develop Alzheimer's disease. "Because I'm collaborating with the Leber Institute, and they have this mythical brain Bank, now I can look at people's frontal cortex [to study schizophrenia], and I can look at the temporal lobe of the same people," McConnell said.

"So actually now that I really can start to oformlyat card more laborious, forming an Atlas of various areas of the brain in many people."This study has the potential to advance awareness of both neurodegenerative diseases, such as cognitive regression, which haunts us with age, potentially leading to fresh ways of healing.